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A safe and effective COVID-19 vaccine is one of the most important tools we have to end the COVID-19 pandemic. We encourage all SLO County residents to learn more about the vaccine, stay informed, and get the vaccine when it’s your turn – to protect yourself and help end the pandemic. Find the latest local information about the vaccine and what it means for all of us in SLO County.

Based on limited vaccine supply and risk of exposure and serious outcomes from COVID-19, the County of San Luis Obispo is vaccinating residents in phases by appointment only at three clinics in SLO County.

COVID-19 Vaccine Appointments

San Luis Obispo community members who are currently eligible for their first dose of the COVID-19 vaccine can now sign up either online or by phone for the County's new Vaccine Appointment Registry.    

Get an Appointment

Latest News

Read the latest local vaccine news releases