Announcement on April 27, 2021: County Resumes Administration of Johnson & Johnson Vaccine 

On April 24, the Western States Scientific Safety Review Workgroup concluded the Johnson & Johnson vaccine is safe and effective and recommended resuming use of the vaccine for all eligible Californians. This is consistent with the findings of the CDC and FDA. The San Luis Obispo County Public Health department is resuming administering the Johnson & Johnson COVID-19 vaccine locally, in accordance with guidance from the California Department of Public HealthRead the full news release here. 

For more information on the Johnson & Johnson Vaccine, visit:  

Currently Available Vaccine

Three vaccines have currently received FDA emergency-use authorization and are available in the U.S.: the Pfizer-BioNTech COVID-19 Vaccine, the Moderna COVID-19 Vaccine, and the Johnson & Johnson COVID-19 Vaccine. 

These three vaccines are similar in important ways: 

  • Rigorous testingAll three vaccines have been through a rigorous testing and review process nationally and additionally by the Western States Scientific Safety Review Workgroup, and the State of California. 

  • Highly effective. Current research shows all three vaccines are incredibly effective at prevent severe illness, hospitalization, and death from COVID-19. 

  • Common mild side effects. People have experienced common mild side effects from all three vaccines, such as pain at the site of the injection and headache or chills for a few days after getting the vaccine. 

  • No live virus. None of the three authorized vaccine contains the SARS-CoV-2 virus. The vaccines cannot give you COVID-19. 

The vaccines are also different in some ways: 

  • Type of vaccineThe COVID-19 vaccines from Pfizer and Moderna are bothmRNA vaccines that provide an instruction manual for your immune system to develop antibodies that will fight the virus that causes COVID-19. The COVID-19 vaccine from Johnson & Johnson is a viral vector vaccine, which uses an inactivated cold virus as a shuttle to deliver the instruction manual for your immune system to develop antibodies against COVID-19. All three vaccines do not contain the live SARS-CoV-2 virus and cannot infect you with COVID-19. 

  • Number of doses. Both the Pfizer and Moderna vaccines are administered in two doses, several weeks apart. The Johnson & Johnson vaccine is administered in a single-dose. 

  • Age when you can get the vaccine. The Pfizer vaccine has received FDA emergency-use authorization to prevent COVID-19 in people 12 years old and older, while the Moderna and Johnson & Johnson vaccines have received such authorization for those 18 years and older. 

Due to the limited and quickly-changing supply of vaccines and the complexity involved in distributing it, we are not able to provide an option to choose which of the authorized vaccines you will to receive at a County vaccine site.  


For more information on the Moderna COVID-19 Vaccine, visit:
For more information on the Pfizer-BioNTech COVID-19 Vaccine, visit:
For more information on the Johnson & Johnson Vaccine, visit: 

U.S. Food and Drug Administration Emergency Use Authorization of Johnson & Johnson COVID-19 Vaccine 

What to expect after getting a vaccine

Myth-Busting COVID-19 Rumors (Spanish)